M. Vertzoni: search on Z-Library

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1

Sensitive and simple liquid chromatographic method with ultraviolet detection for the determination of nifedipine in canine plasma

M.V. Vertzoni, C. Reppas, H.A. Archontaki

Journal:

Analytica Chimica Acta

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

2

Dissolution media simulating the intralumenal composition of the small intestine: physiological issues and practical aspects

Maria Vertzoni, Nikoletta Fotaki, Eleftheria Nicolaides, Christos Reppas, Edmund Kostewicz, Erika Stippler, Christian Leuner, Jennifer Dressman

Journal:

Journal of Pharmacy and Pharmacology

Year:

2004

Language:

english

File:

PDF, 364 KB

english, 2004

3

Biorelevant in-vitro performance testing of orally administered dosage forms

Christos Reppas, Maria Vertzoni

Journal:

Journal of Pharmacy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 343 KB

english, 2012

4

In-vitro simulation of luminal conditions for evaluation of performance of oral drug products: Choosing the appropriate test media

Markopoulos, Constantinos, Andreas, Cord J., Vertzoni, Maria, Dressman, Jennifer, Reppas, Christos

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2015

Language:

english

File:

PDF, 1.35 MB

english, 2015

5

In vitro models for the prediction of in vivo performance of oral dosage forms: recent progress from partnership through the IMI OrBiTo collaboration

Butler, James, Hens, Bart, Vertzoni, Maria, Brouwers, Joachim, Berben, Philippe, Dressman, Jennifer, Andreas, Cord J., Julia Schaefer, Kerstin, Mann, James, McAllister, Mark, Jamei, Masoud, Kostewicz,

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2018

Language:

english

File:

PDF, 2.35 MB

english, 2018

6

Drug supersaturation in simulated and human intestinal fluids representing different nutritional states

Jan Bevernage, Joachim Brouwers, Sarah Clarysse, Maria Vertzoni, Jan Tack, Pieter Annaert, Patrick Augustijns

Journal:

Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 291 KB

english, 2010

7

Biorelevant Media to Simulate Fluids in the Ascending Colon of Humans and Their Usefulness in Predicting Intracolonic Drug Solubility

Maria Vertzoni, Amalia Diakidou, Manos Chatzilias, Erik Söderlind, Bertil Abrahamsson, Jennifer B. Dressman, Christos Reppas

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 380 KB

english, 2010

8

Predicting the oral absorption of a poorly soluble, poorly permeable weak base using biorelevant dissolution and transfer model tests coupled with a physiologically based pharmacokinetic model

Christian Wagner, Ekarat Jantratid, Filippos Kesisoglou, Maria Vertzoni, Christos Reppas, Jennifer B. Dressman

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2012

Language:

english

File:

PDF, 604 KB

english, 2012

9

An in vitro biorelevant gastrointestinal transfer (BioGIT) system for forecasting concentrations in the fasted upper small intestine: Design, implementation, and evaluation

Kourentas, Alexandros, Vertzoni, Maria, Stavrinoudakis, Nick, Symillidis, Alexandros, Brouwers, Joachim, Augustijns, Patrick, Reppas, Christos, Symillides, Mira

Journal:

European Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 832 KB

english, 2016

10

Mechanistic investigation of the negative food effect of modified release zolpidem

Andreas, Cord J., Pepin, Xavier, Markopoulos, Constantinos, Vertzoni, Maria, Reppas, Christos, Dressman, Jennifer B.

Journal:

European Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 2.60 MB

english, 2017

11

Evaluation of Dissolution in the Lower Intestine and Its Impact on the Absorption Process of High Dose Low Solubility Drugs

Georgaka, Danai, Butler, James, Kesisoglou, Filippos, Reppas, Christos, Vertzoni, Maria

Journal:

Molecular Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 3.80 MB

english, 2017

12

Evaluating the clinical importance of bacterial degradation of therapeutic agents in the lower intestine of adults using adult fecal material

Vertzoni, Maria, Kersten, Elisabeth, van der Mey, Dorina, Muenster, Uwe, Reppas, Christos

Journal:

European Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 926 KB

english, 2018

13

Toward the establishment of a standardized pre-clinical porcine model to predict food effects – Case studies on fenofibrate and paracetamol

Henze, Laura J., Koehl, Niklas J., O'Shea, Joseph P., Holm, René, Vertzoni, Maria, Griffin, Brendan T.

Journal:

International Journal of Pharmaceutics: X

Year:

2019

Language:

english

File:

PDF, 775 KB

english, 2019

14

Measuring pH and Buffer Capacity in Fluids Aspirated from the Fasted Upper Gastrointestinal Tract of Healthy Adults

Litou, Chara, Psachoulias, Dimitrios, Vertzoni, Maria, Dressman, Jennifer, Reppas, Christos

Journal:

Pharmaceutical Research

Year:

2020

Language:

english

File:

PDF, 932 KB

english, 2020

15

Successful Extrapolation of Paracetamol Exposure from Adults to Infants After Oral Administration of a Pediatric Aqueous Suspension Is Highly Dependent on the Study Dosing Conditions

Statelova, Marina, Holm, RenÃ©, Fotaki, Nikoletta, Reppas, Christos, Vertzoni, Maria

Journal:

The AAPS Journal

Year:

2020

File:

PDF, 2.13 MB

2020

16

Estimation of intragastric drug solubility in the fed state: comparison of various media with data in aspirates

A. Diakidou, M. Vertzoni, J. Dressman, C. Reppas

Journal:

Biopharmaceutics & Drug Disposition

Year:

2009

Language:

english

File:

PDF, 108 KB

english, 2009

17

Estimating evapotranspiration for a temperate salt marsh, Newcastle, Australia

C. E. Hughes, J. D. Kalma, P. Binning, G. R. Willgoose, M. Vertzonis

Journal:

Hydrological Processes

Year:

2001

Language:

english

File:

PDF, 419 KB

english, 2001

18

Solubilization and quantification of lycopene in aqueous media in the form of cyclodextrin binary systems

Maria Vertzoni, Theodora Kartezini, Christos Reppas, Helen Archontaki, Georgia Valsami

Journal:

International Journal of Pharmaceutics

Year:

2006

Language:

english

File:

PDF, 304 KB

english, 2006

19

Optimized determination of lycopene in canine plasma using reversed-phase high-performance liquid chromatography

M.V. Vertzoni, C. Reppas, H.A. Archontaki

Journal:

Journal of Chromatography B

Year:

2005

Language:

english

File:

PDF, 122 KB

english, 2005

20

Optimization and validation of a high-performance liquid chromatographic method with UV detection for the determination of ketoconazole in canine plasma

M.V. Vertzoni, C. Reppas, H.A. Archontaki

Journal:

Journal of Chromatography B

Year:

2006

Language:

english

File:

PDF, 131 KB

english, 2006

21

Development and validation of a simple reversed-phase high-performance liquid chromatography method for the determination of testosterone in serum of males

V. Loi, M. Vertzoni, A. Vryonidou, C. Phenekos

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2006

Language:

english

File:

PDF, 148 KB

english, 2006

22

Study on the inclusion complexes of bromazepam with β- and β-hydroxypropyl-cyclodextrins

H.A. Archontaki, M.V. Vertzoni, M.H. Athanassiou-Malaki

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2002

Language:

english

File:

PDF, 115 KB

english, 2002

23

Development and optimization of a reversed-phase high-performance liquid chromatographic method for the determination of acetaminophen and its major metabolites in rabbit plasma and urine after a toxic dose

M.V Vertzoni, H.A Archontaki, P Galanopoulou

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2003

Language:

english

File:

PDF, 205 KB

english, 2003

24

Estimation of Intragastric Solubility of Drugs: In What Medium?

Maria Vertzoni, Eleni Pastelli, Dimitris Psachoulias, Lida Kalantzi, Christos Reppas

Journal:

Pharmaceutical Research

Year:

2007

Language:

english

File:

PDF, 332 KB

english, 2007

25

Characterization of the Contents of Ascending Colon to Which Drugs are Exposed After Oral Administration to Healthy Adults

Amalia Diakidou, Maria Vertzoni, Konstantinos Goumas, Erik Söderlind, Bertil Abrahamsson, Jennifer Dressman, Christos Reppas

Journal:

Pharmaceutical Research

Year:

2009

Language:

english

File:

PDF, 198 KB

english, 2009

26

Characterization of the Ascending Colon Fluids in Ulcerative Colitis

Maria Vertzoni, Konstantinos Goumas, Erik Söderlind, Bertil Abrahamsson, Jennifer B. Dressman, Androniki Poulou, Christos Reppas

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 190 KB

english, 2010

27

Precipitation in and Supersaturation of Contents of the Upper Small Intestine After Administration of Two Weak Bases to Fasted Adults

Dimitrios Psachoulias, Maria Vertzoni, Konstantinos Goumas, Vasilios Kalioras, Stefania Beato, James Butler, Christos Reppas

Journal:

Pharmaceutical Research

Year:

2011

Language:

english

File:

PDF, 878 KB

english, 2011

28

Degradation kinetics of metronidazole and olsalazine by bacteria in ascending colon and in feces of healthy adults

Maria Vertzoni, Anders Carlsson, Bertil Abrahamsson, Konstantinos Goumas, Christos Reppas

Journal:

International Journal of Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 367 KB

english, 2011

29

Plasma profiles of lycopene after single oral and intravenous administrations in dogs

Maria Vertzoni, Georgia Valsami, Christos Reppas

Journal:

Journal of Pharmacy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 283 KB

english, 2006

30

Effect of pH and water-soluble polymers on the aqueous solubility of nimesulide in the absence and presence of β-cyclodextrin derivatives

Christina Alexanian, Helen Papademou, Maria Vertzoni, Helen Archontaki, Dr. Georgia Valsami

Journal:

Journal of Pharmacy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 272 KB

english, 2008

31

Stability of oleuropein in the human proximal gut

Constantinos Markopoulos, Maria Vertzoni, Apostolos Agalias, Prokopios Magiatis, Dr Christos Reppas

Journal:

Journal of Pharmacy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 176 KB

english, 2009

32

Estimating drug solubility in the gastrointestinal tract

J.B. Dressman, M. Vertzoni, K. Goumas, C. Reppas

Journal:

Advanced Drug Delivery Reviews

Year:

2007

Language:

english

File:

PDF, 649 KB

english, 2007

33

Simulation of gastric lipolysis and prediction of felodipine release from a matrix tablet in the fed stomach

A. Diakidou, M. Vertzoni, B. Abrahamsson, J. Dressman, C. Reppas

Journal:

European Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 436 KB

english, 2009

34

Application of biorelevant dissolution tests to the prediction of in vivo performance of diclofenac sodium from an oral modified-release pellet dosage form

Ekarat Jantratid, Vincenzo De Maio, Emanuela Ronda, Valentina Mattavelli, Maria Vertzoni, Jennifer B. Dressman

Journal:

European Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 679 KB

english, 2009

35

AnIn VitroMethodology for Forecasting Luminal Concentrations and Precipitation of Highly Permeable Lipophilic Weak Bases in the Fasted Upper Small Intestine

Dimitrios Psachoulias, Maria Vertzoni, James Butler, David Busby, Moira Symillides, Jennifer Dressman, Christos Reppas

Journal:

Pharmaceutical Research

Year:

2012

Language:

english

File:

PDF, 455 KB

english, 2012

36

Simulation of fasting gastric conditions and its importance for the in vivo dissolution of lipophilic compounds

Maria Vertzoni, Jennifer Dressman, James Butler, John Hempenstall, Christos Reppas

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2005

Language:

english

File:

PDF, 120 KB

english, 2005

37

Cogrinding enhances the oral bioavailability of EMD 57033, a poorly water soluble drug, in dogs

Markus Vogt, Maria Vertzoni, Klaus Kunath, Christos Reppas, Jennifer B. Dressman

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2008

Language:

english

File:

PDF, 348 KB

english, 2008

38

Prediction of food effects on the absorption of celecoxib based on biorelevant dissolution testing coupled with physiologically based pharmacokinetic modeling

Yasushi Shono, Ekarat Jantratid, Niels Janssen, Filippos Kesisoglou, Yun Mao, Maria Vertzoni, Christos Reppas, Jennifer B. Dressman

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2009

Language:

english

File:

PDF, 484 KB

english, 2009

39

Biorelevant in vitro dissolution testing of products containing micronized or nanosized fenofibrate with a view to predicting plasma profiles

Daniel Juenemann, Ekarat Jantratid, Christian Wagner, Christos Reppas, Maria Vertzoni, Jennifer B. Dressman

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2011

Language:

english

File:

PDF, 400 KB

english, 2011

40

In vitro vs. canine data for assessing early exposure of doxazosin base and its mesylate salt

Marijana Erceg, Maria Vertzoni, Helena Cerić, Miljenko Dumić, Biserka Cetina-Čižmek, Christos Reppas

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2012

Language:

english

File:

PDF, 738 KB

english, 2012

41

Comparison of simulated cumulative drug versus time data sets with indices

Maria Vertzoni, Mira Symillides, Athanassios Iliadis, Eleftheria Nicolaides, Christos Reppas

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2003

Language:

english

File:

PDF, 255 KB

english, 2003

42

Comparison of the Ascending Colon Fluids in Ulcerative Colitis Patients in Relapse Versus Remission

Constantinos Goumas, Maria Vertzoni, Erik Söderlind, Bertil Abrahamsson, Jennifer B. Dressman, Androniki Poulou, Christos Reppas

Journal:

Gastrointestinal Endoscopy

Year:

2009

Language:

english

File:

PDF, 41 KB

english, 2009

43

Luminal Lipid Phases after Administration of a Triglyceride Solution of Danazol in the Fed State and Their Contribution to the Flux of Danazol Across Caco-2 Cell Monolayers

Vertzoni, Maria, Markopoulos, Constantinos, Symillides, Moira, Goumas, Constantinos, Imanidis, Georgios, Reppas, Christos

Journal:

Molecular Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 398 KB

english, 2012

44

Intestinal permeability and excretion into bile control the arrival of amlodipine into the systemic circulation after oral administration

Dragica Raušl, Nikoletta Fotaki, Ružica Zanoški, Maria Vertzoni, Biserka Cetina-Čižmek, M. Zahirul I. Khan, Christos Reppas

Journal:

Journal of Pharmacy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 244 KB

english, 2006

45

In VitroandEx VivoInvestigation of the Impact of Luminal Lipid Phases on Passive Permeability of Lipophilic Small Molecules Using PAMPA

Markopoulos, Constantinos, Imanidis, Georgios, Vertzoni, Maria, Symillides, Mira, Parrott, Neil, Reppas, Christos

Journal:

Pharmaceutical Research

Year:

2013

Language:

english

File:

PDF, 272 KB

english, 2013

46

Biorelevant media for transport experiments in the Caco-2 model to evaluate drug absorption in the fasted and the fed state and their usefulness

Markopoulos, C., Thoenen, F., Preisig, D., Symillides, M., Vertzoni, M., Parrott, N., Reppas, C., Imanidis, G.

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

47

Comparison of in vitro tests at various levels of complexity for the prediction of in vivo performance of lipid-based formulations: Case studies with fenofibrate

Griffin, Brendan T., Kuentz, Martin, Vertzoni, Maria, Kostewicz, Edmund S., Fei, Yang, Faisal, Waleed, Stillhart, Cordula, O’Driscoll, Caitriona M., Reppas, Christos, Dressman, Jennifer B.

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.61 MB

english, 2014

48

Insights into Intermediate Phases of Human Intestinal Fluids Visualized by Atomic Force Microscopy and Cryo-Transmission Electron Microscopy ex Vivo

Müllertz, Anette, Fatouros, Dimitrios G., Smith, James R., Vertzoni, Maria, Reppas, Christos

Journal:

Molecular Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 4.51 MB

english, 2012

49

1 H NMR Monitoring of the Canine Metabolic Profile after Oral Administration of Xenobiotics Using Multivariate Statistics

Constantinou, Maria A., Vertzoni, Maria, Reppas, Christos, Tsantili-Kakoulidou, Anna, Mikros, Emmanuel

Journal:

Molecular Pharmaceutics

Year:

2007

Language:

english

File:

PDF, 301 KB

english, 2007

50

Gastrointestinal transfer: In vivo evaluation and implementation in in vitro and in silico predictive tools

Hens, Bart, Brouwers, Joachim, Anneveld, Bart, Corsetti, Maura, Symillides, Mira, Vertzoni, Maria, Reppas, Christos, Turner, David B., Augustijns, Patrick

Journal:

European Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 1.04 MB

english, 2014